The Gene Therapy and Regenerative Medicine (GTRM) Unit includes three core staff scientists with distinct research areas and a Vector and Cell Processing core. The goal of the unit is to develop novel therapies using gene therapy and genome editing, immunotherapy, stem cell transplantation and pluripotent stem cells. These therapies are aimed at a large variety of diseases including hematologic malignancies, genetic diseases such as hemoglobinopathies, HIV and cardiac diseases.
The unit currently includes three core investigators with many national and international collaborators and affiliates who maintain active research programs in the following areas:
- Gene Therapy and Genome editing
- Stem Cell Biology
- Stem Cell Transplantation
- Cardiovascular Disease & Tissue Engineering
- Cell and Gene Therapy applications for infections, genetic, and malignant diseases
- Basic & Applied Adenovirus Research
Core Staff Scientists & Affiliates
| Name | WaNPRC Unit | Position | UW Department(s) |
|---|---|---|---|
| Hans-Peter Kiem | Gene Therapy and Regenerative Medicine | Chief - Core Scientist | Department of Medicine: Oncology and Pathology |
| André Lieber | Gene Therapy and Regenerative Medicine | Core Scientist | Department of Medicine: Medical Genetics Pathology |
| Christopher Peterson | Gene Therapy and Regenerative Medicine | GTRM Affiliate, Co-director: Vector and Cell Processing Core (VCPC) | Department of Medicine: Oncology |
Research Core and Fee-For-Service Support
The Vector and Cell Processing Core (VCPC) offers vector-based gene therapy resources for a range of nonhuman primate studies. This core also develops new technologies, platforms and reagents to improve vector production and modification of diverse nonhuman primate cell types.
VCPC provides:
- Viral vectors
- Viral titer assessment
- Pre-validated control vectors and assays to detect virus replication
- Ready-to-use nonhuman primate cells
- Gene-modified cell products for T cell and stem cell applications